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Drug Interaction and Side Effects of CBD

Updated: Oct 7, 2021

CBD has gained immense popularity as it has proved to ease off symptoms of chronic pain, mental health issues, and several other health issues. CBD is safe, with no potential side effects. However, CBD can interact with various potential drugs. Consult a doctor if you are suffering from any severe disease and using over-the counter-medications for that.

Drug Interaction

Every substance that we intake is broken down in the gut, but the liver also plays a crucial role in assimilating drugs. The body produces an enzyme called cytochrome P450 that works on foreign objects. This enzyme metabolizes the supplements and medication that we take. There are many variants of this enzyme family that metabolizes the cannabinoids. However, CBD also interferes with the Cytochrome 3A4. If CBD inhibits the working of this enzyme, the overall metabolism of other drugs in the body is also effective.

Interaction of CBD with other drugs

You must have heard about the grapefruit warning. Certain medications, including CBD, should not be consumed with grapefruit and grapefruit juice. It will create a high concentration of the medicine in the blood resulting in an overdose. Grapefruit also inhibits CYP3A4 and slows the metabolism of various medications.

Watch out for side effects

First things first. Always ask your doctor’s advice before taking any medicine, including CBD. You may experience the following side effects there is an adverse drug interaction.

  1. The overdose of drugs may cause sedation, nausea, and drowsiness.

  2. CBD may cause changes in weight, appetite, diarrhea, and fatigue.

  3. CBD is generally very well tolerated by most people. However, consult your doctor immediately if there are any side effects.

Choose the best product

The quality of the CBD product dictates the effectivity and risks associated with the drug. Studies have shown that the CBD products available online contain less the described dose of CBD. In addition to this, THC was also found in some of them. Make sure that you buy the CBD product from and reputable source to escape any potential health hazards. Always buy FDA approved products to stay safe and healthy.,but%20this%20is%20less%20common.

CBD Drug interactions
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